Computational Drug Repositioning for Peripheral Arterial Disease: Prediction of anti-inflammatory and pro-angiogenic therapeutics

Peripheral arterial disease (PAD) results from atherosclerosis that leads to blocked arteries and reduced blood flow, most commonly in the arteries of the legs.PAD clinical trials to induce angiogenesis to improve blood Knife Sharpening Stones flow conducted in the last decade have not succeeded.We have recently constructed PADPIN, protein-protein

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Detainees, staff, and health care services in immigration detention centres: a descriptive comparison of detention systems in Sweden and in the Benelux countries

Background: Immigration detention has been shown to negatively affect the health and well-being of detainees.The aim of the study was to describe and compare policies and practices that could affect the health and well-being of immigrant detainees in the Benelux countries (Belgium, the Netherlands, and Luxembourg) to those in Sweden.Design: This wa

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Hands-On Reading: The Pioneer Book Club

In 2007, the Rockbridge Regional Library began an Aluminum Cutting Disc association with Boxerwood Nature Center and Woodland Garden in Rockbridge County, Virginia.Our goal was to create programs that encouraged children to read, while also getting them outdoors to enjoy nature.Bonnie Bernstein and Hannah Klein from Boxerwood helped us to create th

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Formal reasoning about systems biology using theorem proving.

System biology provides the basis to understand the behavioral properties of complex biological organisms at different levels of abstraction.Traditionally, analysing systems biology based models of various diseases have been carried out by paper-and-pencil based proofs and simulations.However, these methods cannot provide an accurate analysis, whic

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